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OSTEON-500

Calcium & Vitamin has very strong relationship. Calcium is needed for our heart, muscles, and nerves to function properly and for blood to clot. Inadequate calcium significantly contributes to the development of osteoporosis. Many published studies show that low calcium intake throughout life is associated with low bone mass and high fracture rates. National nutrition surveys have shown that most people are not getting the calcium they need to grow and maintain healthy bones. Wherever the body also needs vitamin D to absorb calcium. Without enough vitamin D, one can’t form enough of the hormone calcitriol (known as the “active vitamin D”). This in turn leads to insufficient calcium absorption from the diet OSTEON-500 provides 100% RDA (Recommended Daily Allowance) of calcium carefully combined with co-factors, vitamin D.

For Doctors
Formulation

Each Uncoated tablet contains:

1250 mg calcium carbonate from an

inorganic sources of Oyster shell

eq. to elemental calcium…….500 mg

Vitamin D3 …………………………..250 IU

Mechanism of action

Absorption Calcium carbonate: About 15-25% gets absorbed in the GI tract. Converted to calcium chloride by gastric acid. Vitamin D well-absorbed in the GI tract in the presence of bile.

Distribution The vast majority of total body calcium (>99%) is present in the skeleton as calcium-phosphate complexes, primarily as hydroxyapatite. Vitamin D binds to receptors located throughout the body.

Excretion   Calcium leaves body in faeces mainly. vitamin D and metabolites are mainly excreted in the bile and faeces.

Indication

During the active phase of growth and development of the skeleton

 I.e. childhood, adolescence and early adulthood; pregnancy and lactation

Prevention and treatment of osteoporosis, particularly in women after menopause and elderly men;

Fractures and immobilization due to prolonged illness;

Long-term steroid therapy

Premenstrual syndrome

Dietary deficiencies i.e. malnutrition and weight-control dieting.

Dosages & Administration

Two Tablets per day with a main meal in divided dose. Swallow with water or a cold drink. Not to be chewed. Do not exceed the recommended intake. OSTEON-500 can be continued for as long as required.

Adverse Drug Reaction

OSTEON-500  is absolutely safe & side effects may rarely occur like  Diarrhea nausea/vomiting, loss of appetite, unusual weight loss, mental/mood changes, change in the amount of urine, bone/muscle pain, headache, increased thirst, increased urination, weakness, tiredness, fast/pounding heartbeat. It also may cause chills and fever, gastrointestinal distress, sore throat, ulcers or sores in the mouth or throat and fatigue and weakness. A very serious allergic reaction to this drug is rare. However give immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Drug Interaction

Calcium can decrease the absorption of other drugs such as tetracycline antibiotics (e.g., doxycycline, minocycline), bisphosphonates (e.g., alendronate), estramustine, levothyroxine, and quinolone antibiotics (e.g., ciprofloxacin, levofloxacin). Also, certain medications can decrease the absorption of vitamin D (bile acid sequestrants such as cholestyramine/colestipol, mineral oil, orlistat). Therefore, separate your doses of these medications as far as possible from your doses of calcium/vitamin D. Ask your doctor or pharmacist about how long you should wait between doses and for help finding a dosing schedule that will work with all your medications. Vitamin D is very similar to calcitriol. Do not use medications containing calcitriol while using vitamin D.

Warning & Precaution

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other vitamin D products (such as calcitriol); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Avoid this medicine in high calcium/vitamin D levels (hypercalcemia/hypervitaminosis D).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart/blood vessel disease, kidney stones, kidney disease, certain immune system disorder (sarcoidosis), liver disease, certain bowel diseases (Crohn's disease, Whipple's disease), little or no stomach acid (achlorhydria), low levels of bile, untreated phosphate imbalance.This medication passes into breast milk. Consult your doctor before breast-feeding. Magnesium should be given very cautiously in the presence of serious impairment of renal function since it is excreted almost entirely by the kidneys

Product and Presentation

Tablet / 15’s / 54.00

For Patients
What is Osteon-500 (calcium and vitamin D) combination?

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of your body, especially bone formation and maintenance.

Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Calcium and vitamin D combination is used to prevent or to treat a calcium deficiency.

Why is it important to get enough OSTEON-500(calcium and vitamin D)?

Your body needs vitamin D to absorb calcium. Calcium keeps your bones and muscles—including your heart—healthy and strong. People who do not get enough calcium and vitamin D throughout life have an increased chance of having thin and brittle bones (osteoporosis) in their later years. Thin and brittle bones break easily and can lead to serious injuries. This is why it is important for you to get enough calcium and vitamin D as a child and as an adult. It helps keep your bones strong as you get older and protects against possible breaks. Your body also uses vitamin D to help your muscles absorb calcium and work well. If your muscles don't get enough calcium, then they can cramp, hurt, or feel weak. You may have long-term (chronic) muscle aches and pains. Getting enough vitamin D helps prevent these problems.
Children who don't get enough vitamin D may not grow as much as others their age. They also have a chance of getting a rare disease called rickets, which causes weak bones.